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TERT promoter mutation associated with multifocal phenotype and poor prognosis in patients with IDH wild-type glioblastoma
BACKGROUND: Although mutations in the promoter region of the telomerase reverse transcriptase (TERTp) gene are the most common alterations in glioblastoma (GBM), their clinical significance remains unclear. Therefore, we investigated the impact of TERTp status on patient outcome and clinicopathologi...
Autores principales: | Kikuchi, Zensho, Shibahara, Ichiyo, Yamaki, Tetsu, Yoshioka, Ema, Shofuda, Tomoko, Ohe, Rintaro, Matsuda, Ken-ichiro, Saito, Ryuta, Kanamori, Masayuki, Kanemura, Yonehiro, Kumabe, Toshihiro, Tominaga, Teiji, Sonoda, Yukihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586143/ https://www.ncbi.nlm.nih.gov/pubmed/33134923 http://dx.doi.org/10.1093/noajnl/vdaa114 |
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