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Arctiin Antagonizes Triptolide-Induced Hepatotoxicity via Activation of Nrf2 Pathway

Triptolide (TP) is the most effective ingredient found in the traditional Chinese herbal Tripterygium wilfordii Hook F, and it is widely used in therapies of autoimmune and inflammatory disorders. However, the hepatotoxicity induced by TP has restricted its use in clinical trials. Arctiin is known a...

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Detalles Bibliográficos
Autores principales: Zhou, Yuyan, Xia, Li, Yao, Weiqiang, Han, Jun, Wang, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586171/
https://www.ncbi.nlm.nih.gov/pubmed/33123566
http://dx.doi.org/10.1155/2020/2508952