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A Comparison of Automated Perfusion- and Manual Diffusion-Based Human Regulatory T Cell Expansion and Functionality Using a Soluble Activator Complex

Absence or reduced frequency of human regulatory T cells (Tregs) can limit the control of inflammatory responses, autoimmunity, and the success of transplant engraftment. Clinical studies indicate that use of Tregs as immunotherapeutics would require billions of cells per dose. The Quantum® Cell Exp...

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Detalles Bibliográficos
Autores principales: Jones, Mark, Nankervis, Brian, Roballo, Kelly Santos, Pham, Huong, Bushman, Jared, Coeshott, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586259/
https://www.ncbi.nlm.nih.gov/pubmed/32662685
http://dx.doi.org/10.1177/0963689720923578