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Deciphering the Relationship Between the Trough Concentration of Posaconazole and Its Efficacy and Safety in Chinese Patients With Hematological Disorders

Posaconazole (PCZ) is effective in preventing and salvage treatment invasive fungal infections in patients with hematologic disorders. However, PCZ displays highly variable individual pharmacokinetics affecting its efficacy and safety. To investigate the correlation between PCZ concentration and eff...

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Detalles Bibliográficos
Autores principales: Jia, Meng-Meng, Zhang, Qi-Wen, Qin, Zi-Fei, Lu, Run-Qing, Tian, Xue-Ke, Yang, Jing, Zhang, Xiao-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586309/
https://www.ncbi.nlm.nih.gov/pubmed/33154724
http://dx.doi.org/10.3389/fphar.2020.575463