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CircECE1 activates energy metabolism in osteosarcoma by stabilizing c-Myc

BACKGROUND: Osteosarcoma (OS) is the most common malignant bone tumor and has a poor prognosis. The potential involvement of circular RNAs (circRNAs) in OS progression remains unexplored. Here, we report that CircECE1, a circular RNA derived from human ECE1, plays a critical role in energy metabolis...

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Detalles Bibliográficos
Autores principales: Shen, Shuying, Yao, Teng, Xu, Yining, Zhang, Deguang, Fan, Shunwu, Ma, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586679/
https://www.ncbi.nlm.nih.gov/pubmed/33106166
http://dx.doi.org/10.1186/s12943-020-01269-4