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Systemic dendrimer-drug nanomedicines for long-term treatment of mild-moderate cerebral palsy in a rabbit model

BACKGROUND: Neuroinflammation mediated by microglia plays a central role in the pathogenesis of perinatal/neonatal brain injury, including cerebral palsy (CP). Therapeutics mitigating neuroinflammation potentially provide an effective strategy to slow the disease progression and rescue normal brain...

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Detalles Bibliográficos
Autores principales: Zhang, Zhi, Lin, Yi-An, Kim, Soo-Young, Su, Lilly, Liu, Jinhuan, Kannan, Rangaramanujam M., Kannan, Sujatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586697/
https://www.ncbi.nlm.nih.gov/pubmed/33100217
http://dx.doi.org/10.1186/s12974-020-01984-1