Ionic Mechanisms of Disopyramide Prolonging Action Potential Duration in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1

Short QT syndrome (SQTS) is associated with tachyarrhythmias and sudden cardiac death. So far, only quinidine has been demonstrated to be effective in patients with SQTS type 1(SQTS1). The aim of this study was to investigate the mechanisms of disopyramide underlying its antiarrhythmic effects in SQ...

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Detalles Bibliográficos
Autores principales: Lan, Huan, Xu, Qiang, El-Battrawy, Ibrahim, Zhong, Rujia, Li, Xin, Lang, Siegfried, Cyganek, Lukas, Borggrefe, Martin, Zhou, Xiaobo, Akin, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586889/
https://www.ncbi.nlm.nih.gov/pubmed/33154722
http://dx.doi.org/10.3389/fphar.2020.554422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586889/
https://www.ncbi.nlm.nih.gov/pubmed/33154722
http://dx.doi.org/10.3389/fphar.2020.554422

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