Mapping developmental trajectories and subtype diversity of normal and glaucomatous human retinal ganglion cells by single‐cell transcriptome analysis

Glaucoma is characterized by a progressive degeneration of retinal ganglion cells (RGCs), leading to irreversible vision loss. Currently, there is no effective treatment for RGC degeneration. We used a disease‐in‐a‐dish stem cell model to examine the developmental susceptibility of RGCs to glaucomat...

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Detalles Bibliográficos
Autores principales: Teotia, Pooja, Niu, Meng, Ahmad, Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586941/
https://www.ncbi.nlm.nih.gov/pubmed/32557945
http://dx.doi.org/10.1002/stem.3238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586941/
https://www.ncbi.nlm.nih.gov/pubmed/32557945
http://dx.doi.org/10.1002/stem.3238

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