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Mapping developmental trajectories and subtype diversity of normal and glaucomatous human retinal ganglion cells by single‐cell transcriptome analysis
Glaucoma is characterized by a progressive degeneration of retinal ganglion cells (RGCs), leading to irreversible vision loss. Currently, there is no effective treatment for RGC degeneration. We used a disease‐in‐a‐dish stem cell model to examine the developmental susceptibility of RGCs to glaucomat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586941/ https://www.ncbi.nlm.nih.gov/pubmed/32557945 http://dx.doi.org/10.1002/stem.3238 |