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Synthesis and Metabolic Fate of 4‐Methylthiouridine in Bacterial tRNA
Ribonucleic acid (RNA) is central to many life processes and, to fulfill its function, it has a substantial chemical variety in its building blocks. Enzymatic thiolation of uridine introduces 4‐thiouridine (s(4)U) into many bacterial transfer RNAs (tRNAs), which is used as a sensor for UV radiation....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586944/ https://www.ncbi.nlm.nih.gov/pubmed/32394608 http://dx.doi.org/10.1002/cbic.202000272 |