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Synthesis and Metabolic Fate of 4‐Methylthiouridine in Bacterial tRNA

Ribonucleic acid (RNA) is central to many life processes and, to fulfill its function, it has a substantial chemical variety in its building blocks. Enzymatic thiolation of uridine introduces 4‐thiouridine (s(4)U) into many bacterial transfer RNAs (tRNAs), which is used as a sensor for UV radiation....

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Detalles Bibliográficos
Autores principales: Borek, Christoph, Reichle, Valentin F., Kellner, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586944/
https://www.ncbi.nlm.nih.gov/pubmed/32394608
http://dx.doi.org/10.1002/cbic.202000272

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