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Multimodal single‐cell analysis reveals distinct radioresistant stem‐like and progenitor cell populations in murine glioma

Radiation therapy is part of the standard of care for gliomas and kills a subset of tumor cells, while also altering the tumor microenvironment. Tumor cells with stem‐like properties preferentially survive radiation and give rise to glioma recurrence. Various techniques for enriching and quantifying...

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Detalles Bibliográficos
Autores principales: Alexander, Jes, LaPlant, Quincey C., Pattwell, Siobhan S., Szulzewsky, Frank, Cimino, Patrick J., Caruso, Francesca P., Pugliese, Pietro, Chen, Zhihong, Chardon, Florence, Hill, Andrew J., Spurrell, Cailyn, Ahrendsen, Dakota, Pietras, Alexander, Starita, Lea M., Hambardzumyan, Dolores, Iavarone, Antonio, Shendure, Jay, Holland, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586969/
https://www.ncbi.nlm.nih.gov/pubmed/32621641
http://dx.doi.org/10.1002/glia.23866