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On the mechanism of protein supercharging in electrospray ionisation mass spectrometry: Effects on charging of additives with short- and long-chain alkyl constituents with carbonate and sulphite terminal groups

Small organic molecules are used as solution additives in electrospray ionisation mass spectrometry (ESI-MS) to increase the charge states of protein ions and improve the performance of intact protein analysis by tandem mass spectrometry. The properties of the additives that are responsible for thei...

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Detalles Bibliográficos
Autores principales: Foley, Eric D.B., Zenaidee, Muhammad A., Tabor, Rico F., Ho, Junming, Beves, Jonathon E., Donald, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587038/
https://www.ncbi.nlm.nih.gov/pubmed/33186415
http://dx.doi.org/10.1016/j.acax.2018.100004