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Evidence for Missing Positive Results for Human Papilloma Virus 45 (HPV-45) and HPV-59 with the SPF(10)-DEIA-LiPA(25) (Version 1) Platform Compared to Type-Specific Real-Time Quantitative PCR Assays and Impact on Vaccine Effectiveness Estimates

Human papillomavirus (HPV) epidemiological and vaccine studies require highly sensitive HPV detection systems. The widely used broad-spectrum SPF(10)-DEIA-LiPA(25) (SPF(10) method) has reduced sensitivity toward HPV-45 and -59. Therefore, anogenital samples from the PASSYON study were retrospectivel...

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Detalles Bibliográficos
Autores principales: van Eer, Kahren, Leussink, Suzan, Severs, Tim T., van Marm-Wattimena, Naomi, Woestenberg, Petra J., Bogaards, Johannes A., King, Audrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587105/
https://www.ncbi.nlm.nih.gov/pubmed/32907991
http://dx.doi.org/10.1128/JCM.01626-20