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Validated Reversed-Phase Liquid Chromatographic Method with Gradient Elution for Simultaneous Determination of the Antiviral Agents: Sofosbuvir, Ledipasvir, Daclatasvir, and Simeprevir in Their Dosage Forms

A simple, rapid, sensitive, and precise reversed-phase liquid chromatographic method was developed and validated for the simultaneous determination of four direct-acting antivirals, sofosbuvir (SF), ledipasvir (LD), declatasvir (DC), and simeprevir (SM), in their respective pharmaceutical formulatio...

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Detalles Bibliográficos
Autores principales: Ezzeldin, Essam, Abo-Talib, Nisreen F., Tammam, Marwa H., Asiri, Yousif A., Amr, Abd El-Galil E., Almehizia, Abdulrahman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587186/
https://www.ncbi.nlm.nih.gov/pubmed/33050433
http://dx.doi.org/10.3390/molecules25204611