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Imipramine Inhibits Migration and Invasion in Metastatic Castration-Resistant Prostate Cancer PC-3 Cells via AKT-Mediated NF-κB Signaling Pathway

Imipramine (IMI) is a tricyclic synthetic antidepressant that is used to treat chronic psychiatric disorders, including depression and neuropathic pain. IMI also has inhibitory effects against various cancer types, including prostate cancer; however, the mechanism of its anticancer activity is not w...

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Detalles Bibliográficos
Autores principales: Lim, Eun Yeong, Park, Joon, Kim, Yun Tai, Kim, Min Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587212/
https://www.ncbi.nlm.nih.gov/pubmed/33050597
http://dx.doi.org/10.3390/molecules25204619