Pimarane Diterpenoids from the Seeds of Caesalpinia minax as PTP1B Inhibitors and Insulin Sensitizers

Protein-tyrosine phosphatase 1B (PTP1B) has been considered as a promising target for treating insulin resistance. In searching for naturally occurring PTB1B antagonists, two new pimarane diterpenoids, named 2α-hydroxy-7-oxo-pimara-8(9),15-diene (1) and 19-hydroxy-2α-acetoxy-7-oxo-pimara-8(9),15-die...

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Detalles Bibliográficos
Autores principales: Xu, Yunshao, Feng, Zheling, Zhang, Tian, Lv, Peng, Cao, Jun, Li, Dan, Peng, Cheng, Lin, Ligen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587383/
https://www.ncbi.nlm.nih.gov/pubmed/33066298
http://dx.doi.org/10.3390/molecules25204674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587383/
https://www.ncbi.nlm.nih.gov/pubmed/33066298
http://dx.doi.org/10.3390/molecules25204674

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