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Pimarane Diterpenoids from the Seeds of Caesalpinia minax as PTP1B Inhibitors and Insulin Sensitizers
Protein-tyrosine phosphatase 1B (PTP1B) has been considered as a promising target for treating insulin resistance. In searching for naturally occurring PTB1B antagonists, two new pimarane diterpenoids, named 2α-hydroxy-7-oxo-pimara-8(9),15-diene (1) and 19-hydroxy-2α-acetoxy-7-oxo-pimara-8(9),15-die...
Autores principales: | Xu, Yunshao, Feng, Zheling, Zhang, Tian, Lv, Peng, Cao, Jun, Li, Dan, Peng, Cheng, Lin, Ligen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587383/ https://www.ncbi.nlm.nih.gov/pubmed/33066298 http://dx.doi.org/10.3390/molecules25204674 |
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