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Antibody Neutralization of HIV-1 Crossing the Blood-Brain Barrier

HIV-1 can cross the blood-brain barrier (BBB) to penetrate the brain and infect target cells, causing neurocognitive disorders as a result of neuroinflammation and brain damage. Here, we examined whether antibodies targeting the HIV-1 envelope glycoproteins interfere with the transcytosis of virions...

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Detalles Bibliográficos
Autores principales: Lorin, Valérie, Danckaert, Anne, Porrot, Françoise, Schwartz, Olivier, Afonso, Philippe V., Mouquet, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587443/
https://www.ncbi.nlm.nih.gov/pubmed/33082263
http://dx.doi.org/10.1128/mBio.02424-20