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Impaired phagocytic function in CX3CR1(+) tissue‐resident skeletal muscle macrophages prevents muscle recovery after influenza A virus‐induced pneumonia in old mice

Skeletal muscle dysfunction in survivors of pneumonia disproportionately affects older individuals in whom it causes substantial morbidity. We found that skeletal muscle recovery was impaired in old compared with young mice after influenza A virus‐induced pneumonia. In young mice, recovery of muscle...

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Detalles Bibliográficos
Autores principales: Runyan, Constance E., Welch, Lynn C., Lecuona, Emilia, Shigemura, Masahiko, Amarelle, Luciano, Abdala‐Valencia, Hiam, Joshi, Nikita, Lu, Ziyan, Nam, Kiwon, Markov, Nikolay S., McQuattie‐Pimentel, Alexandra C., Piseaux‐Aillon, Raul, Politanska, Yuliya, Sichizya, Lango, Watanabe, Satoshi, Williams, Kinola J.N., Budinger, G. R. Scott, Sznajder, Jacob I., Misharin, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587460/
https://www.ncbi.nlm.nih.gov/pubmed/32720752
http://dx.doi.org/10.1111/acel.13180