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Impaired phagocytic function in CX3CR1(+) tissue‐resident skeletal muscle macrophages prevents muscle recovery after influenza A virus‐induced pneumonia in old mice
Skeletal muscle dysfunction in survivors of pneumonia disproportionately affects older individuals in whom it causes substantial morbidity. We found that skeletal muscle recovery was impaired in old compared with young mice after influenza A virus‐induced pneumonia. In young mice, recovery of muscle...
Autores principales: | Runyan, Constance E., Welch, Lynn C., Lecuona, Emilia, Shigemura, Masahiko, Amarelle, Luciano, Abdala‐Valencia, Hiam, Joshi, Nikita, Lu, Ziyan, Nam, Kiwon, Markov, Nikolay S., McQuattie‐Pimentel, Alexandra C., Piseaux‐Aillon, Raul, Politanska, Yuliya, Sichizya, Lango, Watanabe, Satoshi, Williams, Kinola J.N., Budinger, G. R. Scott, Sznajder, Jacob I., Misharin, Alexander V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587460/ https://www.ncbi.nlm.nih.gov/pubmed/32720752 http://dx.doi.org/10.1111/acel.13180 |
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