Investigation of Dextran-Coated Superparamagnetic Nanoparticles for Targeted Vinblastine Controlled Release, Delivery, Apoptosis Induction, and Gene Expression in Pancreatic Cancer Cells

In the current study, the surface of superparamagnetic iron oxide (SPION) was coated with dextran (DEX), and conjugated with folic acid (FA), to enhance the targeted delivery and uptake of vinblastine (VBL) in PANC-1 pancreatic cancer cells. Numerous analyses were performed to validate the prepared...

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Detalles Bibliográficos
Autores principales: Albukhaty, Salim, Al-Musawi, Sharafaldin, Abdul Mahdi, Salih, Sulaiman, Ghassan M., Alwahibi, Mona S., Dewir, Yaser Hassan, Soliman, Dina A., Rizwana, Humaira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587551/
https://www.ncbi.nlm.nih.gov/pubmed/33076247
http://dx.doi.org/10.3390/molecules25204721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587551/
https://www.ncbi.nlm.nih.gov/pubmed/33076247
http://dx.doi.org/10.3390/molecules25204721

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