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Mechanism of Type IA Topoisomerases

Topoisomerases in the type IA subfamily can catalyze change in topology for both DNA and RNA substrates. A type IA topoisomerase may have been present in a last universal common ancestor (LUCA) with an RNA genome. Type IA topoisomerases have since evolved to catalyze the resolution of topological ba...

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Detalles Bibliográficos
Autores principales: Dasgupta, Tumpa, Ferdous, Shomita, Tse-Dinh, Yuk-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587558/
https://www.ncbi.nlm.nih.gov/pubmed/33080770
http://dx.doi.org/10.3390/molecules25204769