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Mechanism of Type IA Topoisomerases
Topoisomerases in the type IA subfamily can catalyze change in topology for both DNA and RNA substrates. A type IA topoisomerase may have been present in a last universal common ancestor (LUCA) with an RNA genome. Type IA topoisomerases have since evolved to catalyze the resolution of topological ba...
Autores principales: | Dasgupta, Tumpa, Ferdous, Shomita, Tse-Dinh, Yuk-Ching |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587558/ https://www.ncbi.nlm.nih.gov/pubmed/33080770 http://dx.doi.org/10.3390/molecules25204769 |
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