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Molecular Dynamic Simulations to Probe Stereoselectivity of Tiagabine Binding with Human GAT1
The human gamma aminobutyric acid transporter subtype 1 (hGAT1) located in the nerve terminals is known to catalyze the neuronal function by the electrogenic reuptake of γ-aminobutyric acid (GABA) with the co-transport of Na(+) and Cl(−) ions. In the past, there has been a major research drive focus...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587590/ https://www.ncbi.nlm.nih.gov/pubmed/33081136 http://dx.doi.org/10.3390/molecules25204745 |