Affinity of Antifungal Isoxazolo[3,4-b]pyridine-3(1H)-Ones to Phospholipids in Immobilized Artificial Membrane (IAM) Chromatography

Currently, rapid evaluation of the physicochemical parameters of drug candidates, such as lipophilicity, is in high demand owing to it enabling the approximation of the processes of absorption, distribution, metabolism, and elimination. Although the lipophilicity of drug candidates is determined usi...

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Detalles Bibliográficos
Autores principales: Ciura, Krzesimir, Fedorowicz, Joanna, Žuvela, Petar, Lovrić, Mario, Kapica, Hanna, Baranowski, Paweł, Sawicki, Wiesław, Wong, Ming Wah, Sączewski, Jarosław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587931/
https://www.ncbi.nlm.nih.gov/pubmed/33092252
http://dx.doi.org/10.3390/molecules25204835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587931/
https://www.ncbi.nlm.nih.gov/pubmed/33092252
http://dx.doi.org/10.3390/molecules25204835

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