Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance

Human immunodeficiency virus 1 (HIV-1) infection is a global health issue since neither a cure nor a vaccine is available. However, the highly active antiretroviral therapy (HAART) has improved the life expectancy for patients with acquired immunodeficiency syndrome (AIDS). Nucleoside reverse transc...

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Detalles Bibliográficos
Autores principales: Bertoletti, Nicole, Chan, Albert H., Schinazi, Raymond F., Anderson, Karen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587939/
https://www.ncbi.nlm.nih.gov/pubmed/33096918
http://dx.doi.org/10.3390/molecules25204868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587939/
https://www.ncbi.nlm.nih.gov/pubmed/33096918
http://dx.doi.org/10.3390/molecules25204868

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