Topological Regulation of the Bioactive Conformation of a Disulfide-Rich Peptide, Heat-Stable Enterotoxin

Heat-stable enterotoxin (ST(a)) produced by enterotoxigenic E. coli causes acute diarrhea and also can be used as a specific probe for colorectal cancer cells. ST(a) contains three intra-molecular disulfide bonds (C1–C4, C2–C5, and C3–C6 connectivity). The chemical synthesis of ST(a) provided not on...

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Detalles Bibliográficos
Autores principales: Shimamoto, Shigeru, Fukutsuji, Mayu, Osumi, Toi, Goto, Masaya, Toyoda, Hiroshi, Hidaka, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587965/
https://www.ncbi.nlm.nih.gov/pubmed/33096591
http://dx.doi.org/10.3390/molecules25204798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587965/
https://www.ncbi.nlm.nih.gov/pubmed/33096591
http://dx.doi.org/10.3390/molecules25204798

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