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Copper Transporters? Glutathione Reactivity of Products of Cu–Aβ Digestion by Neprilysin
[Image: see text] Aβ(4–42) is the major subspecies of Aβ peptides characterized by avid Cu(II) binding via the ATCUN/NTS motif. It is thought to be produced in vivo proteolytically by neprilysin, but in vitro experiments in the presence of Cu(II) ions indicated preferable formation of C-terminally t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588031/ https://www.ncbi.nlm.nih.gov/pubmed/32212682 http://dx.doi.org/10.1021/acs.inorgchem.0c00427 |