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Alternative isoforms of KDM2A and KDM2B lysine demethylases negatively regulate canonical Wnt signaling

A precisely balanced activity of canonical Wnt signaling is essential for a number of biological processes and its perturbation leads to developmental defects or diseases. Here, we demonstrate that alternative isoforms of the KDM2A and KDM2B lysine demethylases have the ability to negatively regulat...

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Detalles Bibliográficos
Autores principales: Lađinović, Dijana, Pinkas, Daniel, Šopin, Tijana, Raška, Otakar, Liška, František, Raška, Ivan, Vacík, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588095/
https://www.ncbi.nlm.nih.gov/pubmed/33104714
http://dx.doi.org/10.1371/journal.pone.0236612