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Effects of Integrase Inhibitor–Based ART on the NLRP3 Inflammasome Among ART-Naïve People With HIV

The NOD-like receptor protein family pyrin domain containing 3 (NLRP3) inflammasome, activated in the setting of HIV, contributes to pro-atherogenic inflammation. Among antriretroviral therapy–naïve people with HIV (vs controls), levels of caspase-1—a key component of the NLRP3 inflammasome—were sig...

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Detalles Bibliográficos
Autores principales: Toribio, Mabel, Burdo, Tricia H, Fulda, Evelynne S, Cetlin, Madeline, Chu, Sarah M, Feldpausch, Meghan N, Robbins, Gregory K, Neilan, Tomas G, Melbourne, Kathleen, Grinspoon, Steven K, Zanni, Markella V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588107/
https://www.ncbi.nlm.nih.gov/pubmed/33134423
http://dx.doi.org/10.1093/ofid/ofaa459