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E2 ubiquitin-conjugating enzyme UBE2L6 promotes Senecavirus A proliferation by stabilizing the viral RNA polymerase

Senecavirus A (SVA), discovered in 2002, is an emerging pathogen of swine that has since been reported in numerous pork producing countries. To date, the mechanism of SVA replication remains poorly understood. In this study, utilizing iTRAQ analysis we found that UBE2L6, an E2 ubiquitin-conjugating...

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Detalles Bibliográficos
Autores principales: Li, Liang, Bai, Juan, Fan, Hui, Yan, Junfang, Li, Shihai, Jiang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588118/
https://www.ncbi.nlm.nih.gov/pubmed/33104725
http://dx.doi.org/10.1371/journal.ppat.1008970