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Aprepitant, an antiemetic agent, interferes with metal ion homeostasis of Candida auris and displays potent synergistic interactions with azole drugs

With the rapid increase in the frequency of azole-resistant species, combination therapy appears to be a promising tool to augment the antifungal activity of azole drugs against resistant Candida species. Here, we report the effect of aprepitant, an antiemetic agent, on the antifungal activities of...

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Detalles Bibliográficos
Autores principales: Eldesouky, Hassan E., Lanman, Nadia A., Hazbun, Tony R., Seleem, Mohamed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588212/
https://www.ncbi.nlm.nih.gov/pubmed/33100149
http://dx.doi.org/10.1080/21505594.2020.1838741