Resveratrol exerts antitumor effects by downregulating CD8(+)CD122(+) Tregs in murine hepatocellular carcinoma
CD4(+)Foxp3(+) regulatory T cells (Tregs) in the tumor microenvironment restrain antitumor immunity, resulting in tumor aggression and poor survival in hepatocellular carcinoma (HCC). CD8(+)CD122(+) Tregs have been previously shown to be more potent in immunosuppression than are CD4(+)Foxp3(+) Tregs...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588216/ https://www.ncbi.nlm.nih.gov/pubmed/33150044 http://dx.doi.org/10.1080/2162402X.2020.1829346 |