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A mutation in C. neoformans mitochondrial NADH dehydrogenase results in increased virulence in mice

Cryptococcus neoformans: (H99W) was serially passaged in the invertebrate wax moth Galleria mellonella fifteen times to study how fungal virulence evolves under selection and whether those adaptations affect virulence. The G. mellonella passaged strain (P15) and the pre-passage H99W strains were use...

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Detalles Bibliográficos
Autores principales: Merryman, Mitch, Crigler, Jacob, Seipelt-Thiemann, Rebecca, McClelland, Erin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588220/
https://www.ncbi.nlm.nih.gov/pubmed/33103620
http://dx.doi.org/10.1080/21505594.2020.1831332