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Molecular mechanism for direct actin force-sensing by α-catenin

The actin cytoskeleton mediates mechanical coupling between cells and their tissue microenvironments. The architecture and composition of actin networks are modulated by force; however, it is unclear how interactions between actin filaments (F-actin) and associated proteins are mechanically regulate...

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Detalles Bibliográficos
Autores principales: Mei, Lin, Espinosa de los Reyes, Santiago, Reynolds, Matthew J, Leicher, Rachel, Liu, Shixin, Alushin, Gregory M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588232/
https://www.ncbi.nlm.nih.gov/pubmed/32969337
http://dx.doi.org/10.7554/eLife.62514