Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers

Filoviruses such as Ebola and Marburg virus bud from the host membrane as enveloped virions. This process is achieved by the matrix protein VP40. When expressed alone, VP40 induces budding of filamentous virus-like particles, suggesting that localization to the plasma membrane, oligomerization into...

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Detalles Bibliográficos
Autores principales: Wan, William, Clarke, Mairi, Norris, Michael J, Kolesnikova, Larissa, Koehler, Alexander, Bornholdt, Zachary A, Becker, Stephan, Saphire, Erica Ollmann, Briggs, John AG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588233/
https://www.ncbi.nlm.nih.gov/pubmed/33016878
http://dx.doi.org/10.7554/eLife.59225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588233/
https://www.ncbi.nlm.nih.gov/pubmed/33016878
http://dx.doi.org/10.7554/eLife.59225

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