Modifiers of Adeno-Associated Virus-Mediated Gene Expression in Implication for Serotype-Universal Neutralizing Antibody Assay

Adeno-associated virus (AAV)-based gene therapy is undergoing major expansion into clinical practice, with two treatments currently being granted Food and Drug Administration (FDA) approval. However, the presence of pre-existing neutralizing antibodies (NAB) is one of the significant hurdles for the...

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Detalles Bibliográficos
Autores principales: Krotova, Karina, Aslanidi, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Protocol—Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588322/
https://www.ncbi.nlm.nih.gov/pubmed/32495655
http://dx.doi.org/10.1089/hum.2020.074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588322/
https://www.ncbi.nlm.nih.gov/pubmed/32495655
http://dx.doi.org/10.1089/hum.2020.074

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