Cargando…
High-throughput synthetic rescue for exhaustive characterization of suppressor mutations in human genes
Inherited or acquired mutations can lead to pathological outcomes. However, in a process defined as synthetic rescue, phenotypic outcome created by primary mutation is alleviated by suppressor mutations. An exhaustive characterization of these mutations in humans is extremely valuable to better comp...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588364/ https://www.ncbi.nlm.nih.gov/pubmed/32270227 http://dx.doi.org/10.1007/s00018-020-03519-6 |