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EVI1 oncoprotein expression and CtBP1-association oscillate through the cell cycle

Aberrantly high expression of EVI1 in acute myeloid leukaemia (AML) is associated with poor prognosis. For targeted treatment of EVI1 overexpressing AML a more detailed understanding of aspects of spatiotemporal interaction dynamics of the EVI1 protein is important. EVI1 overexpressing SB1690CB AML...

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Detalles Bibliográficos
Autores principales: Paredes, Roberto, Schneider, Marion, Pearson, Stella, Teng, Hsiang Yin, Kelly, James R., Pierce, Andrew, Somervaille, Tim C. P., Whetton, Anthony D., Meyer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588369/
https://www.ncbi.nlm.nih.gov/pubmed/32979164
http://dx.doi.org/10.1007/s11033-020-05829-1