TP63 links chromatin remodeling and enhancer reprogramming to epidermal differentiation and squamous cell carcinoma development

Squamous cell carcinoma (SCC) is an aggressive malignancy that can originate from various organs. TP63 is a master regulator that plays an essential role in epidermal differentiation. It is also a lineage-dependent oncogene in SCC. ΔNp63α is the prominent isoform of TP63 expressed in epidermal cells...

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Detalles Bibliográficos
Autores principales: Yi, Mei, Tan, Yixin, Wang, Li, Cai, Jing, Li, Xiaoling, Zeng, Zhaoyang, Xiong, Wei, Li, Guiyuan, Li, Xiayu, Tan, Pingqing, Xiang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588389/
https://www.ncbi.nlm.nih.gov/pubmed/32447427
http://dx.doi.org/10.1007/s00018-020-03539-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588389/
https://www.ncbi.nlm.nih.gov/pubmed/32447427
http://dx.doi.org/10.1007/s00018-020-03539-2

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