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Mutant CFTR Drives TWIST1 mediated epithelial–mesenchymal transition

Cystic fibrosis (CF) is a monogenetic disease resulting from mutations in the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene encoding an anion channel. Recent evidence indicates that CFTR plays a role in other cellular processes, namely in development, cellular differentiation and w...

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Detalles Bibliográficos
Autores principales: Quaresma, Margarida C., Pankonien, Ines, Clarke, Luka A., Sousa, Luís S., Silva, Iris A. L., Railean, Violeta, Doušová, Tereza, Fuxe, Jonas, Amaral, Margarida D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588414/
https://www.ncbi.nlm.nih.gov/pubmed/33106471
http://dx.doi.org/10.1038/s41419-020-03119-z