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GSK-3β activation is required for ZIP-induced disruption of learned fear

The myristoylated zeta inhibitory peptide (ZIP), which was originally developed as a protein kinase C/Mζ (PKCζ/PKMζ) inhibitor, is known to produce the loss of different forms of memories. However, ZIP induces memory loss even in the absence of PKMζ, and its mechanism of action, therefore, remains e...

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Detalles Bibliográficos
Autores principales: Song, Sukwoon, Kim, Jihye, Park, Kyungjoon, Lee, Junghwa, Park, Sewon, Lee, Sukwon, Kim, Jeongyeon, Hong, Ingie, Song, Beomjong, Choi, Sukwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588416/
https://www.ncbi.nlm.nih.gov/pubmed/33106552
http://dx.doi.org/10.1038/s41598-020-75130-5