Establishment and application of a novel method based on single nucleotide polymorphism analysis for detecting β-globin gene cluster deletions

β-Globin gene mutations reduce or terminate the production of beta globin chains, of which approximately 10% are large deletions within the β-globin gene cluster. Because gene deletion leads to loss of heterozygosity at single nucleotide polymorphism (SNP), a novel method for detecting β-globin gene...

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Detalles Bibliográficos
Autores principales: Hu, Siqi, Zhan, Wenli, Wang, Jicheng, Xie, Jia, Zhou, Weiping, Yang, Xiaohan, Zeng, Yukun, Hu, Tingting, Duan, Lei, Chen, Keyi, Du, Li, Yin, Aihua, Luo, Mingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588424/
https://www.ncbi.nlm.nih.gov/pubmed/33106596
http://dx.doi.org/10.1038/s41598-020-75507-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588424/
https://www.ncbi.nlm.nih.gov/pubmed/33106596
http://dx.doi.org/10.1038/s41598-020-75507-6

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