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Optimization of T4 phage engineering via CRISPR/Cas9

A major limitation hindering the widespread use of synthetic phages in medical and industrial settings is the lack of an efficient phage-engineering platform. Classical T4 phage engineering and several newly proposed methods are often inefficient and time consuming and consequently, only able to pro...

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Detalles Bibliográficos
Autores principales: Duong, Michelle M., Carmody, Caitlin M., Ma, Qinqin, Peters, Joseph E., Nugen, Sam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588440/
https://www.ncbi.nlm.nih.gov/pubmed/33106580
http://dx.doi.org/10.1038/s41598-020-75426-6