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Optimization of T4 phage engineering via CRISPR/Cas9
A major limitation hindering the widespread use of synthetic phages in medical and industrial settings is the lack of an efficient phage-engineering platform. Classical T4 phage engineering and several newly proposed methods are often inefficient and time consuming and consequently, only able to pro...
Autores principales: | Duong, Michelle M., Carmody, Caitlin M., Ma, Qinqin, Peters, Joseph E., Nugen, Sam R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588440/ https://www.ncbi.nlm.nih.gov/pubmed/33106580 http://dx.doi.org/10.1038/s41598-020-75426-6 |
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