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E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow

The migration of many cell types relies on the formation of actomyosin-dependent protrusions called blebs, but the mechanisms responsible for focusing this kind of protrusive activity to the cell front are largely unknown. Here, we employ zebrafish primordial germ cells (PGCs) as a model to study th...

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Detalles Bibliográficos
Autores principales: Grimaldi, Cecilia, Schumacher, Isabel, Boquet-Pujadas, Aleix, Tarbashevich, Katsiaryna, Vos, Bart Eduard, Bandemer, Jan, Schick, Jan, Aalto, Anne, Olivo-Marin, Jean-Christophe, Betz, Timo, Raz, Erez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588466/
https://www.ncbi.nlm.nih.gov/pubmed/33106478
http://dx.doi.org/10.1038/s41467-020-19114-z