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E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow
The migration of many cell types relies on the formation of actomyosin-dependent protrusions called blebs, but the mechanisms responsible for focusing this kind of protrusive activity to the cell front are largely unknown. Here, we employ zebrafish primordial germ cells (PGCs) as a model to study th...
Autores principales: | Grimaldi, Cecilia, Schumacher, Isabel, Boquet-Pujadas, Aleix, Tarbashevich, Katsiaryna, Vos, Bart Eduard, Bandemer, Jan, Schick, Jan, Aalto, Anne, Olivo-Marin, Jean-Christophe, Betz, Timo, Raz, Erez |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588466/ https://www.ncbi.nlm.nih.gov/pubmed/33106478 http://dx.doi.org/10.1038/s41467-020-19114-z |
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