Modeling of variables in cellular infection reveals CXCL10 levels are regulated by human genetic variation and the Chlamydia-encoded CPAF protease

Susceptibility to infectious diseases is determined by a complex interaction between host and pathogen. For infections with the obligate intracellular bacterium Chlamydia trachomatis, variation in immune activation and disease presentation are regulated by both host genetic diversity and pathogen im...

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Detalles Bibliográficos
Autores principales: Schott, Benjamin H., Antonia, Alejandro L., Wang, Liuyang, Pittman, Kelly J., Sixt, Barbara S., Barnes, Alyson B., Valdivia, Raphael H., Ko, Dennis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588472/
https://www.ncbi.nlm.nih.gov/pubmed/33106516
http://dx.doi.org/10.1038/s41598-020-75129-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588472/
https://www.ncbi.nlm.nih.gov/pubmed/33106516
http://dx.doi.org/10.1038/s41598-020-75129-y

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