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Modeling of variables in cellular infection reveals CXCL10 levels are regulated by human genetic variation and the Chlamydia-encoded CPAF protease
Susceptibility to infectious diseases is determined by a complex interaction between host and pathogen. For infections with the obligate intracellular bacterium Chlamydia trachomatis, variation in immune activation and disease presentation are regulated by both host genetic diversity and pathogen im...
Autores principales: | Schott, Benjamin H., Antonia, Alejandro L., Wang, Liuyang, Pittman, Kelly J., Sixt, Barbara S., Barnes, Alyson B., Valdivia, Raphael H., Ko, Dennis C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588472/ https://www.ncbi.nlm.nih.gov/pubmed/33106516 http://dx.doi.org/10.1038/s41598-020-75129-y |
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